Modified mRNA (modRNA)

Modified mRNA (modRNA) is a synthetic messenger RNA engineered with chemical modifications—such as pseudouridine or 5-methylcytidine—to enhance stability, reduce innate immune response, and improve translational efficiency in vivo. It enables transient expression of therapeutic proteins or antigens directly in target tissues without the risk of genomic integration. modRNA is ideal for gene therapy, protein replacement, and mRNA-based vaccine applications, providing a safe and efficient method for delivering genetic instructions to cells within the body.